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Nuria Pérez Álvarez


Biostatistician
Fundació de Lluita contra la SIDA (FLS) at Hospital Universitari Germans Trias i Pujol

Assistant professor
Statistics and Operations Research Department of Universitat Politècnica de Catalunya



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Research Areas

Clinical Trials
Longitudinal data analysis
Pharmacoeconomics

Education:

MSc in Biostatistics, Hasselt Universiteit, November 2006
MSc in Statistics, Universitat Politècnica de Catalunya, July 2005
BA in Statistics, Universitat Politècnica de Catalunya, July 2001

Current Projects:


  • Research Project: ‘Métodos avanzados de análisis de supervivencia en estadística genética’ (MTM2008-06747-C02-01/MTM). Funded by: Ministerio de Educación y Ciencia. Participants: Universitat Politècnica de Catalunya, Universidad de Vic. PI: Guadalupe Gómez Melis. Duration: October 2008-October 2011.
  • Research Project: Consolidate group ‘Modelización Estadístico Multivariante y Computacional’ (2009 SGR 932). Funded by: Generalitat de Catalunya. PI: Carles Cuadras. Duration: 2009-2012.

Selection of Publications:


  • Bonjoch A, Bayés B, Riba J, Puig J, Estany C, Perez-Alvarez N, Clotet B, Negredo E. (2010 Dec.). Validation of estimated renal function measurements compared with the isotopic glomerular filtration rate in an HIVinfected cohort. Antiviral Res. 88(3):347-54.
  • Bonjoch A, Figueras M, Estany C, Perez-Alvarez N, Rosales J, del Rio L, di Gregorio S, Puig J, Gómez G, Clotet B, Negredo E; Osteoporosis Study Group. (2010 Nov). High prevalence of and progression to low bone mineral density in HIV-infected patients: a longitudinal cohort study. AIDS.24(18):2827-33.
  • Aparicio E, Parera M, Franco S, Perez-Alvarez N, Tural C, Clotet B, Martinez MA. (2010 Oct.). IL28B SNP rs8099917 is strongly associated with pegylated interferon-alpha and ribavirin therapy treatment failure in HCV-HIV-1-coinfected patients. Antiviral Therapy 29;15:96.
  • Massanella M, Negredo E, Perez-Alvarez N, Puig J, Ruiz-Hernández R, Bofill M, Clotet B, Blanco J. (2010 Apr). CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART. AIDS. 24;24(7):959-68.
  • Negredo E, Massanella M, Puig J, Perez-Alvarez N,Gallego-Escuredo JM, Villarroya J, Villarroya F, Moltó J, Santos JR, Clotet B, Blanco J. (2010). Nadir CD4 T cell count as predictor and high CD4 T cell intrinsic apoptosis as final mechanism of poor CD4 T cell recovery in virologically suppressed HIV-infected patients: clinical implications. Clin Infect Dis; 50(9): 1300-1308.

Research Areas:

Clinical Trials

Protocol design and sample size calculation

Statistical Analysis and results report

 

Longitudinal Data

Longitudinal continuous and politomous data analysis

Missing data analysis

 

Pharmacoeconomics

Pharmacoeconomic models

Decision models

 

Contact:

Universitat Politècnica de Catalunya
Departament d'Estadística i Investigació Operativa
E-mail: nuria.perezARROBAupc.edu